Watched a doc last night about a guy in his 50's seeing various professionals about the best way to reach old age without much risk of heart problems or cancer.
One guy suggested he fast on 50 calories a day, for 4 days straight. Do this once every couple of months.
The presenter did it for 3 1/2 days and his IGF-1 hormone HALVED in that time. The professional said that lower IGF-1 hormone reduces inflammation and puts the body into 'repair mode. His evidence of this was a family in some foreign country whom are basically dwarfs, with inherited very low IGF-1 levels. This family eat chit, smoke, drink, are overweight yet live into very old age with no health problems.
Some extract from a website discussing IGF-1:
This is based mainly on the effect of protein (specially from animal origin) on IGF-1 levels, as high IGF-1 levels have been associated with increased risk of cancer. This was particularly troubling considering that protein intake directly regulates IGF-1 levels: in long term CRONers, a reduction of protein intake was necessary to lower serum IGF-1 levels.
This means that, in contrast to rodents, energy restriction was not sufficient to lower IGF-1. Further evidence of the effects of dietary protein come from studies done on Drosophila, which show that protein (but not energy) restriction was critical for the beneficial effects on longevity. Similar findings in rodents have also been published. I think there are some caveats and nuances to take into account, but that is a topic for another day.
So, in humans, long term CR appears to show most of the health benefits observed in other species, with the exception of lower IGF-1 levels. Thus, the current trend is to restrict protein intake to up to 0.8g/kg of body weight.
So basically to get these benefits you have to reduce protein intake and fast. Thats news to me i've always been lead to believe there is no harm in high protein intake.
In the end the presenter settled on a more reasonable diet, the 5:2, and after 5 weeks had lost 15lb (he wasnt even fat to begin with).
Is this all BS old science, is intermittent fasting basically the most modern version of 5:2 or is it all just wishy washy bro science?
One guy suggested he fast on 50 calories a day, for 4 days straight. Do this once every couple of months.
The presenter did it for 3 1/2 days and his IGF-1 hormone HALVED in that time. The professional said that lower IGF-1 hormone reduces inflammation and puts the body into 'repair mode. His evidence of this was a family in some foreign country whom are basically dwarfs, with inherited very low IGF-1 levels. This family eat chit, smoke, drink, are overweight yet live into very old age with no health problems.
Some extract from a website discussing IGF-1:
This is based mainly on the effect of protein (specially from animal origin) on IGF-1 levels, as high IGF-1 levels have been associated with increased risk of cancer. This was particularly troubling considering that protein intake directly regulates IGF-1 levels: in long term CRONers, a reduction of protein intake was necessary to lower serum IGF-1 levels.
This means that, in contrast to rodents, energy restriction was not sufficient to lower IGF-1. Further evidence of the effects of dietary protein come from studies done on Drosophila, which show that protein (but not energy) restriction was critical for the beneficial effects on longevity. Similar findings in rodents have also been published. I think there are some caveats and nuances to take into account, but that is a topic for another day.
So, in humans, long term CR appears to show most of the health benefits observed in other species, with the exception of lower IGF-1 levels. Thus, the current trend is to restrict protein intake to up to 0.8g/kg of body weight.
So basically to get these benefits you have to reduce protein intake and fast. Thats news to me i've always been lead to believe there is no harm in high protein intake.
In the end the presenter settled on a more reasonable diet, the 5:2, and after 5 weeks had lost 15lb (he wasnt even fat to begin with).
Is this all BS old science, is intermittent fasting basically the most modern version of 5:2 or is it all just wishy washy bro science?
from Bodybuilding.com Forums - Nutrition https://ift.tt/2RkdWEg
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