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The early immune response in a person who has been vaccinated for coronavirus can predict the level of protection they will have to the virus over time, according to analysis from Australian mathematicians, clinicians and scientists published in Nature Medicine, reported UNSW Sydney Newsroom.
The company said it was able to develop the emulsion-based formulation for the drug in-house in just three weeks and has a capacity to manufacture 10,000 vials per day, which will be enough to cater to nearly 6,000 patients per month.
Apart from the B.1.617.2 variant, the B.1.1.7 strain first identified in the United Kingdom has been identified as 'Alpha variant'. The VOCs that were identified in South Africa and Brazil have been named 'Beta' and 'Gamma' respectively.
The RDIF has signed agreements with several companies to manufacture Sputnik V in India — Virchow Biotech (up to 200 million doses per year) Gland Pharma (252 million doses) and Stelis Biopharma (200 million doses).
The government is planning to conduct a study that will see whether a single dose of Covishield provides enough protection against Covid-19. “This could be a new vaccination strategy,” a senior government official said.
At a high-level review meeting on Covid-19, chaired by Chief Minister Y S Jagan Mohan Reddy, the government decided to permit the administration of three traditional drugs, simply named P, L and F.
The Serum Institute of India will make 90 million doses of AstraZeneca in June from about 65 million a month now, a company spokesman told Reuters. Bharat Biotech also plans to ramp up production of its Covaxin vaccine to 23 million in June from about 10 million in April, a government official said.
"Additional 30,100 vials of #Amphotericin-B have been allocated to all the States/UTs and Central Institutions today," the Union Minister for Chemicals and Fertilisers DV Sadananda Gowda tweeted on Monday. He said an additional 1,930 vials of Amphotericin-B has been allocated to Karnataka.
On the occasion of 'World No Tobacco Day', the drug maker has also launched an Artificial Intelligence-enabled chatbot 'Dr Will', which would encourage and support tobacco smokers to quit smoking.
While the evidence linking SARS-CoV-2 to the Wuhan Institute of Virology in China is strictly circumstantial, a number of experts want tougher controls on such facilities over fears that accidental leaks could touch off the next pandemic.
Dr. Reddy's is also in talks with the Indian government and the private sector to supply the two-dose Sputnik V vaccine, which the company expects to commercially launch in the country in the middle of next month.
According to a study conducted by the Pasteur Institute in France, the vaccine developed by Pfizer is slightly less effective but still is able to offer protection against the coronavirus variant found in India.
The experts said surgeons should consider performing a non-urgent surgery on a Covid-recovered patient only after six weeks of recovery to ensure faster healing and convalescence post-surgery.
"We are pleased to inform that in June we will be able to manufacture and supply 9 to 10 crore doses of Covishield to the country as compared to our production capacity of 6.5 crore doses in May," Prakash Singh, the Director of Government and Regulatory Affairs at SII, said.
On May 22, there were 8,848 cases across India according to the central government. By May 26, the total number of cases went up to 11,717, an increase of 2,869 cases in just four days.
Researchers have kept the technology free of intellectual property rights and are looking for pharmaceutical partners who can take up mass-scale production. Currently, AmB is an injectible drug.
While government-owned pharma companies are ailing from years of neglect, some have rolled up their sleeves and joined India’s uphill battle against Covid, with plans to manufacture drugs that are used for treatment of Covid-19 patients or to produce vaccines that can shield people from the dreaded SARS-CoV-2 virus.
Over 167 million people of the over 1,37 billion population have been administered at least one dose of the vaccine, translating to approximately 12.21 per cent coverage or nearly 1 in every 8 Indians getting vaccinated.
"Despite slightly diminished efficacy, the Pfizer vaccine probably protects" against the Indian variant, according to laboratory test results, said Olivier Schwartz, the institute's director and co-author of the study that was published on the BioRxiv website ahead of peer review.
For this, the HNRFH has tied up with Access Life Assistance Foundation, an NGO that provides multi-disciplinary supportive care to families of cancer-afflicted children who come to Mumbai for treatment.
The company has received approval from the US Food and Drug Administration (USFDA) to market in the US its generic version in strengths of 1 mg, 2.5 mg, 5 mg, and 10 mg, Zydus Cadila said in a statement.
Minister of state for chemical and fertilizers Mansukh Mandaviya on Saturday said that the production of Remdesivir has been ramped up ten times from 33,000 vials per day to 3,50,000 vials per day.
While many medicines and treatments were given the A-OK to ease the symptoms, some have been found to be ineffective, especially amid the second wave that has brought in more serious Covid symptoms.
The first batch of DRDO's anti-Covid-19 drug was released on May 17 by Defence Minister Rajnath Singh and health minister Dr Harsh Vardhan, after the Drugs Controller General of India permitted the emergency use authorisation of 2-deoxy-D-glucose (2-DG), anti-viral drug as an adjunct therapy for moderate to severe coronavirus patients.
"Sun Pharma has now acquired the rights to trademarks Oxra, Oxramet and Oxraduo in India from AstraZeneca AB, Sweden, parent company of AstraZeneca Pharma India Limited, with effect from May 28, 2021," Sun Pharma said in a regulatory filing.
As the government has tweaked some guidelines to adjust the timeline of doses and partially vaccinating people, is it a good idea to mix a dose of Covaxin and a dose of Covishield?
AstraZeneca India will continue to independently market Dapagliflozin, the combinations of Dapagliflozin and Metformin as well as Dapagliflozin and Saxagliptin in India under the brand names Forxiga, Xigduo and Qtern respectively, the filing said.
The company has received approval from FDA (Food and Drugs Administration) Gandhi Nagar, Gujarat (India), to manufacture and market Posaconazole API as approved medication for treating Mucormycosis in India, Bajaj Healthcare said in a regulatory filing.
Most states are either adding or earmarking beds for paediatric Covid care, including paediatric intensive care units (PICU), neonatal intensive care units (NICU) and sick newborn care units (SNCU).
Stating facts about Centre’s initiatives to buy vaccines from abroad, Paul said the central government has remained engaged continuously with all the major international vaccine manufacturers right from mid-2020. Multiple rounds of discussions have happened with Pfizer, J&J & Moderna, Paul said.
The high court said the medicine is required to save lives of thousands of people suffering from Mucormycosis and the central government shall seriously consider waiver of customs duty till the drug is in short supply in India.
When it comes to a vaccine, while it could help in preventing an infection, but its not a cure. Moreover, for those who are immunosuppressed- a vaccine isn't an option. So, are there any options in the market?
The Phase-3 of Covid-19 Vaccination has started from May 1. Under the strategy, every month 50 per cent of the total Central Drugs Laboratory (CDL) cleared vaccine doses of any manufacturer would be procured by the Centre. It would continue to make these doses available to state governments free of cost as was being done earlier, the ministry said.
In a regulatory filing Lupin announced "the achievement of key milestones for Lupin's MEK inhibitor compound (LNP3794) that is planned for development by Boehringer Ingelheim in combination as potential targeted therapy for patients with difficult-to-treat cancers."
The vaccine will be developed using Dyadic’s proprietary C1-cell protein production platform. Dyadic is developing what it believes will be a potentially significant biopharmaceutical gene expression platform, based on the fungus Thermothelomyces heterothallica or C1.
According to the National Health Surveillance Agency of Brazil Anvisa, Bharat Biotech made the request on May 25 and a day before the Ministry of Health of the South American country filed a new application for authorisation to import 20 million doses of the Covaxin.
Regeneron and Roche's antibody cocktail has also received emergency use approval in India, and will be distributed by drugmaker Cipla. The first batch of the cocktail became available in the country earlier this week.
According to data available on Our World In Data and multiple sources, other leading countries in COVID-19 vaccination drive include the UK which has reached 5.1 crore mark in 168 days, Brazil that reached 5.9 crore mark in 128 days, and Germany which reached 4.5 crore mark in 149 days.
The Indian Council of Medical Research will review 3,000-5,000 people above 45 years of age, of which up to 80% will be those who have taken the AstraZeneca vaccine made locally by the Serum Institute of India. The rest will have taken Covaxin jointly developed by local firm Bharat Biotech and ICMR.
Kang said that apparently he did not say all vaccinated people will die in two years, as claimed by some, but he did say that new variants are created through selection imposed by antibodies made through vaccination.
The Central Drugs Standard Control Organization has approved the new drug application (NDA) of TLC for Amphotericin B Liposome for Injection 50mg for immediate importation as per approved usage and indication, Zydus Cadila said.
