New study: plant-based, low-fat diet vs animal based keto diet

High quality metabolic ward study by Kevin Hall.

A plant-based, low-fat diet decreases ad libitum energy intake compared to an animal-based, ketogenic diet: An inpatient randomized controlled trial

The PBLF diet resulted in substantially greater glucose and insulin levels whereas the ABLC diet led to increased blood ketones of ~3 mM which is thought to suppress appetite. However, ad libitum energy intake was 689±73 kcal/d lower during the PBLF diet as compared to the ABLC diet (p<0.0001) with no significant differences in appetite ratings or enjoyment of meals. These data challenge the veracity of the carbohydrate-insulin model of obesity and suggest that the PBLF diet had benefits for appetite control whereas the ABLC diet had benefits for lowering blood glucose and insulin.

https://osf.io/preprints/nutrixiv/rdjfb/

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