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Should I keep bulking? (PICTURES)

Sup boys. I uploaded 4 recent photos to my Bodyspace. You can get them clicking my profile, there's 2 flexed and 2 unflexed under progress pictures. The unflexed were taken mid November before the holidays so I'm probably a little bigger now, but the flexed were taken this week.

I bulked all 2022 and I'm seeing results but I don't know if it's been the optimal combo of fat and muscle. Some days I feel chubby, especially if it's at the end of the day and I'm not flexing. In jeans I've gone from a 30 in January to a 34 and even 36 in one pair now which I'm worried about too.

How is my physique looking dudes? Should I continue the bulk in 2023, cut, or maintain? I'd appreciate it if you dropped me a BF% estimate too if you can, though I don't know how much I weigh right now, I'm 6 feet tall if that means anything.

If you need different angles let me know and I'll upload some more.

I HAVE ADDED NEW PHOTOS FROM OVER THE YEAR, JAN, MARCH, APRIL, AND THIS SUMMER


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8 and 12 hour eating windows yield similar myofibrillar protein synthesis

Not sure anyone cares about these types of studies anymore but figured I'd post about this small study just published: https://pubmed.ncbi.nlm.nih.gov/36546330/

They compared an 8-hour eating window (8 male subjects, meals at 10a/2p/6p) to a 12-hour eating window (10 male subjects, meals at 8a/2p/8p). No exercise during the study. Used continuous glucose monitoring that indicated subjects were compliant with meal times. All subjects age 35-55 with BMI 25-35. Attempted to provide sufficient calories for everyone to maintain weight but there was a small amount of weight loss in both groups. Protein was at 1 g/kg/d.

They quantified myofibrillar protein synthesis over 10 days and it was equivalent in both groups. Unclear if/how things would change with a shorter eating window, if actively restricting calories or bulking, if including resistance training, and if women were included.


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What should a 5’5” 130lb female consume to get lean?

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will this lean me up? bf is currently 22%


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Zydus Life receives final USFDA approval for insomnia drug

The approval granted by the US Food and Drug Administration (USFDA) is to market Triazolam tablets of strengths 0.125 mg and 0.25 mg, the company said in a regulatory filing.

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Pharmexcil suspends membership of Marion Biotech for failing to provide information

"You were asked to submit your response by the end of business day of December 29th, 2022. We regret to inform that Council is not in receipt of any inputs/report on the adverse events and hereby state that the membership of Marion Biotech Pvt Ltd with Pharmexcil suspended with immediate effect," Bhaskar added.

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UP Drug Controller finds lapses in Marion Biotech's plant, halts production

The UP Drug Controller who is probing the Marion Biotech's facilities that manufactured the alleged contaminated cough syrup linked to death of 18 children in Uzbekistan, said it has found certain lapses in the compliance to current good manufacturing practices (cGMP) and asked the company to halt manufacturing immediately, a top official of the UP Food Safety and Drug Administration told ET.

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Cough syrup deaths: Marion Biotech into pharma, nutraceuticals, cosmetic products

Founded in 1999, the company is understood to have a presence in Central Asian countries, Central and Latin America, South East Asia, and Africa. It claims to be the brand leader in the categories that it is present in these markets.

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Uzbekistan cough syrup deaths: India's Marion Biotech halts manufacturing, CDSCO initiates probe

"We regret deaths, govt is conducting an enquiry. We'll take action as per the report. Samples were collected. Manufacturing of that product has been halted as of now & other processes are underway," said Hasan Raza, Marion Biotech Pharma Company legal head. ​In a statement, the Uzbek Health Ministry had said that "18 out of 21 children with acute respiratory disease have died as a result of taking Doc-1 Max syrup manufactured by the Indian company Marion Biotech Pvt Ltd".

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Urgent need to develop antibiotics for newborns, say global experts

Over the last decade, AMR has worsened to the point where around 50-70 per cent of common pathogens show a high degree of resistance to available first and second-line antibiotics, they said.

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3 Processed Foods No One Over 40 Should Be Eating Anymore

As we age, our metabolism tends to slow down, making it more difficult to maintain a healthy weight and process the nutrients from our food that help our bodies thrive at their full potential. This is due to a number of factors, including a decrease in muscle mass, hormonal changes, and lower physical activity levels. Luckily, though, there are a few factors that can affect our metabolism that is very much in our control–including our diets. By avoiding processed foods and instead focusing on whole foods, it’s possible to support a faster metabolism and stay fit over time.

Processed foods have become a staple in many people’s diets. Unfortunately, though, these types of foods can take a serious toll on your metabolism in the long run, which is just one reason you should avoid them as much as possible, especially if you want to lose weight or simply avoid weight gain as you age. To learn more about the effects of these foods and discover some of the worst options out there, we spoke to Jesse Feder, RDN, CPT at Strength Warehouse. He pointed out sugary cereal, fast food, and frozen dinners as some of the worst culprits when it comes to your metabolism. Learn more below!


Sugary cereal

As delicious and convenient as they can be, sugary cereals are one processed food that can have negative impacts on your metabolism, according to Feder. "Sugary cereals are one of the most unhealthy processed foods you can have. They are loaded with sugar, sodium, and refined carbohydrates," he says. "These things, when eaten in high amounts and consistently, can lead to obesity, high blood pressure, diabetes, and heart disease. The highly processed and refined ingredients typically give you a jolt of energy since they are able to be digested very quickly. This then causes a crash in our blood sugar, and can slow your metabolism." Yikes!

The high amount of added sugars in this food, in particular, poses a whole range of health risks, including weight gain. When we consume too much sugar, our bodies produce insulin to help process it. This insulin surge can cause our cells to become resistant to the hormone, leading to higher levels of insulin in the bloodstream. High levels of insulin can lead to weight gain, especially around the abdominal area, and have been linked to an increased risk of developing type 2 diabetes and other metabolic disorders. Overall, it’s better to cook yourself a nutritious, balanced breakfast–although it may take more time than pouring cereal and milk into a bowl, it’ll be worth it in the end!

Fast Food

Despite the fact that it’s an extremely convenient option when you’re on the road, Feder warns that fast food can also ruin your metabolism over time. "Fast food meals are made with high amounts of fat, sodium, and unhealthy oils. This can also lead to weight gain, obesity, cardiovascular disease, heart disease, and stroke to name a few things," he says. "The ingredients in fast food meals are also highly processed and refined which can be digested quickly and leave you with a decreased metabolism."

Fast foods, along with many other processed foods, are often high in unhealthy fats, such as trans fats and saturated fats. These types of fats can increase cholesterol levels and contribute to the development of heart disease and other health problems. They can also cause inflammation in the body, which has been linked to a range of health issues, including obesity and metabolic disorders. Of course, desperate times call for desperate measures–and one McDonald’s hamburger won’t kill you. But whenever possible, go with healthier options, like a salad with dressing on the side.

Frozen dinners

Feder says that frozen dinners are some of the worst options out there when it comes to metabolism-slowing processed foods. This is largely due to their high levels of fat and salt. "Frozen dinners typically have large amounts of fat and salt in them to make them taste good as well as keep them preserved. High amounts of fat and salt can lead to weight gain, obesity, high blood pressure, and cardiovascular disease," he explains.

Another problem with this processed food (along with most others) is that it is often low in nutrients and high in empty calories. This means that it provides very few (if any) vitamins, minerals, and other nutrients that our bodies need to function properly. Instead, it’s packed with fillers and additives that have no nutritional value, but can still contribute to weight gain and other health problems. You can still reap the benefits and ease of frozen foods by freezing your own homemade meals to eat later on–but overall, it’s best to steer clear of store-bought varieties.

Overall, it is especially important to be mindful of what you’re eating if you’re over 40, as metabolism tends to slow down as we age. And while there’s a long list of foods that can support metabolism and an equally long list of ones that can slow it down, sugary cereal, frozen dinners, and fast food are all examples of things to avoid. We know cutting these tasty American staples out of your diet can be difficult–and after all, no one is perfect–but keep in mind that making healthy decisions is the best way not only to lose weight, but also to lead a long, happy life.

Source : SHEFiNDS


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Claims against Dr Reddy's over Revlimid in US dismissed

Dr Reddy's Laboratories on Thursday said all claims against it in the antitrust litigation filed in the US, related to a prescription medicine Revlimid, used in treatment of multiple myeloma have been dismissed.

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Now, Uzbekistan links 18 kids' deaths to cough syrup from India

" It was found that the deceased children, before admission to hospital treatment, took this drug at home for 2-7 days 3-4 times a day, 2.5-5 ml, which exceeds the standard dose of the drug for children," the release added.

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Serum Institute to provide 2 crore Covishield doses to central govt free of cost

India has stepped its surveillance and genome sequencing of Covid positive samples. With only 27 per cent of the eligible adult population having taken the precaution dose, government officials have appealed to those due for it to take it.

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Biological E, Bharat Biotech together sitting on stockpile of 250 million COVID vaccine doses

According to respective company sources, Biological E is holding 200 million doses of its COVID-19 vaccine Corbevax while Bharat Biotech is sitting on a stockpile of 50 million doses of Covaxin. Dr Vikram Paradkar, Executive Vice President (Manufacturing), Biological E, said the firm produced about 30 crore doses of Corbevax in total, abiding by the vaccine manufacturing commitment to the Central government.

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India inspects drug factories as Gambia controversy lingers

India is known as the "pharmacy of the world" and its pharmaceuticals exports have more than doubled over the past decade to $24.5 billion in the past fiscal year. The deaths of at least 70 children in Gambia has dented the industry's image, though India says the drugs made by New Delhi-based Maiden Pharmaceuticals Ltd were not at fault.

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Max Healthcare partners with genomics biotech firm Anuva

Max Healthcare on Tuesday said it has entered into a partnership with genomics biotech firm Anuva to conduct genomic-based research on various communicable and non-communicable diseases in India.

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Covid-19 nasal vaccine is here: Price, benefits, all you need to know

Bharat Biotech has finally announced the price of its intra nasal vaccine for Covid-19, the first in the world. Here is the price of Bharat Biotech nasal covid vaccine on CoWin.

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Cipla's higher automation spends to continue for 3 more years: CTO Geena Malhotra

The company, however, did not disclose the financial details of its automation spends. The journey on automation has its roots in a decision Cipla took in 2020, where it started with reimagining technology and making it more cost-effective, Malhotra said, adding that it wanted to align closely with the organisation's view of how it sees itself ten years down the line.

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Government working towards eradication of TB by 2025: MoS Bharati Pawar

Union Minister of State for Health and family welfare Dr. Bharati Pawar inaugurated the medical records room of the department of Clinical Research at ICMR-National Institute of Tuberculosis Research (NIRT) at Chennai.

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Its impossible to get 200g of protein being vegan

Guys!! How will we maintain muscle when meat becomes extinct, we all know governments are trying to ban meat, protein bars and powders are a scam because they made me weaker not stronger

Are governments trying to ban all meat worldwide so we will be too skinny and weak to resist when being arrested for, say, accidentally sneezing on a spider?


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Maiden Pharma syrup caused child deaths: Gambian committee

“The Select Committee is convinced that Maiden Pharmaceuticals Ltd is culpable and should be held accountable for exporting the contaminated medicines that was linked to the death of at least 70 children in The Gambia in 2022,” the Parliamentary panel said in its report.

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Alembic Pharma gets USFDA nod for generic drug to treat breast cancer

The approval granted by the US Food & Drug Administration (USFDA) is for the abbreviated new drug application (ANDA), Fulvestrant injection of strength 250 mg/5 mL (50 mg/mL) per single-dose prefilled syringe, the company said in a statement.

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Advent pips Blackstone, set to buy Suven Pharma for Rs 6300 cr

Announcement expected as early as Monday morning. Open offer if fully subscribed to could make it a $1 bn deal

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Merry Christmas & Happy Holidays to you all

Got back into lifting this year after a break due to Covid. Been good seeing old and newer accounts & friends again.

Have a great day. Been trying to avoid stuffing myself full of chocolate as I'm still cutting...

All the best to you, happy lifting.

Let's hope a mod comes back to clear up the spam soon!


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Advent pips blackstone, set to buy Suven Pharma for ₹6.3kcr

Market capitalisation of Suven Pharma, as on Friday, was ₹12,682.43 crore. ET was the first to report on the sale on December 23. Advent is using Cohance Lifesciences as the vehicle for the acquisition. The platform was created last month for its active pharmaceutical ingredient (API) and contract development and manufacturing businesses comprising three portfolio companies - RA Chem Pharma, ZCL Chemicals and Avra Laboratories.

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Nasal COVID vaccine makes debut, now available on CoWin; dose price yet to be announced



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India recognised as pharmacy of the world: FM Nirmala Sitharaman

She said, "The Centre, along with state governments, executed vaccination at a rapid pace that by the time Omicron variant of Covid attacked us, we were prepared to face it... India could stand up to face the challenge because of the preparedness of a democratically-elected government."

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Mutation is COVID's only tool for outbreak, people should be careful: Expert

Drawing a comparison between India and China, Dr Mishra said that India has strong protection of hybrid immunity due to exposure either symptomatic or asymptomatic and China has not developed that situation.

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Bharat Biotech intranasal vaccine to be available as booster dose for those over 18 in next few weeks

The DCGI (Drugs Controller General of India) gave its go-ahead for the completion of its vaccine trials and the formal announcement about the intranasal vaccine is likely to be made in the next few days, according to sources. ​​​​The nasal vaccine, BBV154 or Incovacc, had last month received a green signal from the Central Drugs Standard Control Organisation (CDSCO) under restricted use in an emergency situation for the 18+ population in India as heterologous booster doses.

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Daiichi seeks forensic audit into transactions between Fortis and group cos

While seeking forensic audit of transactions between the brothers and the Religare Group of companies - Religare Capital Market, Religare Capital Market International (Mauritius), Religare Enterprises, Religare Finvest and Religare Comtrade - Daiichi said the auditor so appointed should be asked to give its final report within 180 days and a retired HC judge should "oversee and supervise" the process.

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Molnupiravir doesn't help reduce deaths or hospital admissions: Study

Previous studies among unvaccinated patients had suggested that molnupiravir could help prevent hospital admission. The latest study provides new evidence that policymakers should consider when formulating their winter Covid-19 strategies, the report said.

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Bharti Airtel, Apollo Hospitals conduct India's first 5G-driven colonoscopy

As per current protocol, colon cancer is detected through a colonoscopy procedure which is manual, requires great attention for accuracy and is time-consuming, taking 30-40 minutes per case.

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Protein-based vaccines must be given a shot: Experts

The supply of protein subunit vaccines as the best booster choice should be increased, Anurag Agrawal, former head of the Indian SARS-CoV-2 Genomics Consortium and chair of the World Health Organization's technical advisory group on virus evolution, told ET

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"Eat Less, Move More" Doesn't Actually Work for Weight Loss, According to a New Study

Absolutely shameless

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https://www.eatingwell.com/article/8...oss-new-study/


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Pharmaceutical companies step up hiring of sales representatives to expand market share

Industry executives and headhunters told ET that salesforce is needed as they launch more products targeting chronic therapeutic segments such as diabetes, heart failure, central nervous system and respiratory. In addition, they said, companies are focusing on going beyond metro and tier-1 cities and engaging as many prescribers and chemists as possible.

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Ujala Cygnus to raise Rs 150 crore from PE investors

Ujala Cygnus is controlled by leading media house Amar Ujala through its healthcare arm Medicive Healthcare. Ghoshal owns 25% in Medicive. Eight Roads Ventures, Evolvence India Fund II and Somerset Indus Capital Partners are other investors, who may exit in the upcoming round.

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Costs of 127 medicines set to go down post NPPA's 5th price cap

Among the 127 medications on the NPPA's list are paracetamol, amoxycillin, rabeprazole, and metformin. Patients frequently make use of many of these. The price of paracetamol (650 mg), which is sold for Rs 2.3 per tablet, has been restricted at Rs 1.8.

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What's your 2022 Christmas dinner?

I've got about half a dozen people coming over.

Menu:

Grilled rib eyes.
Lobster tails.
Crab legs.
Deep fried shrimp.
Cheddar bay biscuits.
French fries.
Hush puppies.

A keg of Modelo.


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Indian pharma sector set for 'volume to value leadership' journey in 2023

While R&D investment, market competitiveness, regulatory scrutiny, and domestic price regulations are expected to shape the growth of generics and injectable products, concerns such as price control and customs duties on medical equipment will continue to bother the healthcare industry in 2023.

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Duty to ensure Covid doesn't spread, questioning me is like obstructing me in my duty: Mansukh Mandaviya

"It is my duty to ensure that Covid doesn't spread in the country. If someone thinks how can a minister question them, then what can we do about their mindset? Questioning me on this is like obstructing me from doing my duty", Mandaviya told the media. He said that several people who joined Rahul Gandhi's Bharat Jodo Yatra have tested positive for Covid, alleging that the Congress is unnecessarily making his letter a political issue.

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Indian pharma sector set for 'volume to value leadership' journey in 2023

While R&D investment, market competitiveness, regulatory scrutiny, and domestic price regulations are expected to shape the growth of generics and injectable products, concerns such as price control and customs duties on medical equipment will continue to bother the healthcare industry in 2023.

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Indian companies are paying up to 25% more for China APIs

Key APIs have become 12-25% costlier in the past few days amid possible supply disruptions that may squeeze margins and raise drug prices, industry executives said. This could also lead to drug shortages, they warned

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Immuneel's CAR-T cell therapy reports positive in early phase-2 trials in India

The early results from the IMAGINE study were based on the first 10 patients of the planned 24 patients to be enrolled.Both adult and children with acute leukemia as well as lymphoma patients post median 2 lines of treatment, including in post-transplant settings were enrolled.

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4.21 crore hospital admissions authorised under PM-JAY till Dec 14: Government

Launched in 2018, AB PM-JAY is the largest publicly funded health insurance scheme which provides a health cover of Rs 5 lakh per family per year for secondary and tertiary care hospitalisation to 10.74 crore poor and vulnerable families.

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Gambia lawmakers say India's Maiden Pharmaceuticals to blame for child kidney injury deaths

A few days ago, India's Central Drug Laboratory (CDL) which carried out tests on the samples from the Sonepat-based company, found the products to be complying with norms, putting the onus on WHO for "prematurely" blaming the company for the deaths without any "independent verification".

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In Mumbai, doctor family's case stirs debate over cough syrups for kids

A press release from the UK's National Health Service in 2017 urged parents to avoid using over-the-counter cough syrups and medicines to treat coughs and colds in children in favour of "old-fashioned" honey and lemon. "A lot of cough and cold medicines contain active ingredients such as nasal decongestants, antihistamines and 'cough suppressors' that may, in large doses, have adverse effects or be toxic if consumed in large quantities,'' it said.

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Can’t eat during 12 hour shift at work

Hi all,

Hope someone can answer my quostion.

I’m working four 12 hour shift a week, the food at work is terrible and I can’t bring my own food. What are your thoughts I should do to get my calories? Should I have couple of protein shakes instead of lunch? Maybe someone is having same issue?


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Viatris cuts price of TB drug by 34%

The decision to cut the price will help to expand access to a critical new treatment in more than 140 countries, including India, which has one of the highest TB burdens. The price reduction will bring both (BPaL and BPaLM closer to $500 per patient course.

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Cadila Pharma appoints Ashraf Allam global COO

Allam, who served as the CEO at the Public Investment Fund prior to joining Cadila Pharmaceuticals, will report to Group Chairman and Managing Director Rajiv Modi, the company said in a statement. Previously he has worked with multinationals such as Johnson & Johnson, Amgen, Eli Lilly, BMS and Mundipharma, it added.

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Former AIIMS Director Randeep Guleria joins Medanta Hospital

Recipient of Padma Shri and Dr B.C. Roy Award, former AIIMS Delhi director is globally renowned for his vast experience and exceptional contribution to India's COVID response effort. He is also associated with the World Health Organization (WHO) as a member of its Scientific Advisory Group of Experts (SAGE) on immunization and influenza vaccination and is part of the editorial boards of several medical journals.

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Dr Reddy's Lab completes Phase 1 study of proposed arthritis drug

Dr Reddy's Laboratories Ltd on Monday said it has successfully completed the Phase 1 study of its proposed biosimilar of Tocilizumab to be used in the treatment of rheumatoid arthritis in adults.

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Glenmark Pharma gets USFDA nod for generic drug

The approval granted by the US Food & Drug Administration (USFDA) is for bicardipine hydrochloride capsules of strengths 20 mg and 30 mg, Glenmark said in a statement.

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WTO Council defers decision on TRIPS waiver extension

"In view of paragraph 8 of the ministerial decision on the TRIPS Agreement adopted on June 17, 2022 providing that no later than six months from the date of this decision, members will decide on its extension to cover the production and supply of Covid-19 diagnostics and therapeutics, the TRIPS Council recommends that the General Council extend the deadline," council Chair, Ambassador Lansana Gberie of Sierra Leone, said in the report on Friday

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Dr Reddy's unit inks pact to sell certain assets of Netherlands-based site

The compensation would be increased by an amount of EUR 1,50,000 upon satisfaction of certain conditions, it added. Post this, no further payment would be made to the purchaser, the drug firm said. Dr Reddy's said it expects the deal to conclude by December 31, 2022.

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'WHO stands by its action on Gambia cough syrup issue'

India had on Thursday said quality tests on the samples lifted from Maiden Pharmaceuticals - which has been in the dock for allegedly causing deaths of children in The Gambia - by the government's Central Drugs Laboratory (CDL) found the products to be in compliance with prescribed specifications and not contaminated with diethylene glycol (DEG) or ethylene glycol (EG).

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Maiden Pharma hopes to reopen plant as Indian lab clears syrups suspected by WHO in Gambia deaths

Indian health authorities halted production at Maiden's main factory in Sonepat near New Delhi in October after a WHO report said the company's cough and cold syrups might be connected to the deaths of 69 children in Gambia this year.

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MHIL to provide up to Rs 300 crore funds to Max Hospitals and Allied Services

Further, the company said its board has also approved the issuance of sponsor's undertaking to the lending bank or financial institutions to Dr Balabhai Nanavati Hospital (BNH) to affirm that it would continue to hold 100 per cent in stake in Max Hospitals and Allied Services Ltd (MHASL) and meet the shortfall arising due to cost and time overruns for the project.

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